Cytotoxic diterpenoid alkaloid from Aconitum japonicum subsp. subcuneatum
نویسندگان
چکیده
منابع مشابه
Crystal structure of sepaconitine, a C19-diterpenoid alkaloid from the roots of Aconitum sinomontanum Nakai
The title compound [systematic name: [(1α,14α,16β)-20-ethyl-8,9,10-trihy-droxy-1,14,16-tri-meth-oxy-aconitan-4-yl 2-amino-benzoate], C30H42N2O8, a natural C19-diterpenoid alkaloid, possesses an aconitane carbon skeleton with four six-membered rings and two five-membered rings. The fused ring system contains two chair, one boat, one twist-boat and two envelope conformations. Intra-molecular N-H⋯...
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Aconitm balfourii (Renunculaceae) is an important highly prized herb found in the Uttaranchal Himalaya in India. It has been frequently used in Ayurvedic systems of medicines since long time but unfortunately it is not taken up of for its systematic chemical investigation after 1928 when an alkaloid was reported to be present in its roots. In our program to search useful high altitude Himalayan...
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Three new bisditerpenoid alkaloids, navicularines A-C (1-3), and three known ones (4-6), were isolated from the ground parts of Aconitum naviculare. Their structures were elucidated by spectroscopic methods. All the new compounds were tested against five cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW480). It was found that navicularine B exhibited certain cytotoxic activities in vitro, with IC5...
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The chemical constituents from Aconitum richardsonianum var. pseudosessiliflorum were investigated. The roots of this plant were extracted three times with 90% EtOH at the room temperature. The ethanol extracts were combined and concentrated under reduced pressure to yield residue, which was suspended in water and successively partitioned with chloroform. The chloroform extraction was isolated ...
متن کاملDiterpenoid alkaloids of Aconitum vulparia Rchb.
From the roots of Aconitum vulparia Rchb., collected in Prüm (Germany), a new norditerpenoid alkaloid, named alexhumboldtine, has been isolated along with the known norditerpenoid alkaloids lappaconitine, anthranoyllycoctonine, lycoctonine, puberaconitine, ajacine, and septentriodine. The structure of alexhumboldtine was established on the basis of 1H, 13C, DEPT, homonuclear 1H COSY, NOESY, HSQ...
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ژورنال
عنوان ژورنال: Journal of Natural Medicines
سال: 2019
ISSN: 1340-3443,1861-0293
DOI: 10.1007/s11418-019-01346-z